BERNAL ANCHUELA FRANCISCO JAVIER,CARRASCAL RIERA MARTA,CATURLA JAVALOYES JUAN FRANCISCO,GRACIA FERRER JORDI,MATASSA VICTOR GIULIO,TERRICABRAS BELART EMMA,TALTAVULL MOLL JOAN,ERRA SOLA MONTSERRAT
申请号:
NZ61408212
公开号:
NZ614082A
申请日:
2012.04.26
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks). In one embodiment the derivative is (S)-2-(1-(9H-purin-6-ylamino)propyl)-3-phenylpyrrolo[1,2-f][1,2,4]triazin-4(3H)-one.