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TRANSPORTEUR DOTE D'UN CAPTEUR DE GLUCOSE POUR DETERMINER LA VIABILITE D'UN ORGANE OU D'UN TISSU
专利权人:
LIFELINE SCIENTIFIC; INC.
发明人:
MAYER, STEVEN L.,KRAVITZ, DAVID C.,MAYER, TRACY H.
申请号:
CA2942689
公开号:
CA2942689A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
An apparatus for perfusing an organ or tissue includes a perfusion circuit and a glucose sensor operatively connected to the perfusion circuit. The glucose sensor is configured to detect a target agent that is an indicator of viability of the organ or tissue. The target agent may be Kidney Injury Molecule-1 (KIM-1). The sensor includes a solid support, such as a bead or membrane, to which is attached a recognition molecule that specifically binds to the target agent but not significantly to other agents. The sensor also includes an enzyme that can catalyze the conversion of a substance to glucose. In the presence of the target agent the enzyme can convert the substance into glucose, which can then be detected and optionally be quantified by the sensor.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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