SANIÈRE LAURENT RAYMOND MAURICE,LABÉGUÈRE FRÉDÉRIC GILBERT,NEWSOME GREGORY JOHN ROBERT,ALVEY LUKE JONATHAN,FLETCHER STEPHEN ROBERT
申请号：
NZ62647312
公开号：
NZ626473A
申请日:
2012.12.20
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
A compound according to Formula (Ia) wherein L1, and G, and R1 are as described herein. The present disclosure relates to compounds that antagonize GPR84, a G-protein-coupled receptor that is involved in inflammatory conditions, and methods for the production of these compounds, pharmaceutical compositions comprising these compounds, and methods for the prevention and/or treatment of inflammatory conditions (for example inflammatory bowel diseases (IBD), rheumatoid arthritis, vasculitis, lung diseases (e.g. chronic obstructive pulmonary disease (COPD) and lung interstitial diseases (e.g. idiopathic pulmonary fibrosis (IPF))), neuroinflammatory conditions, infectious diseases, autoimmune diseases, endocrine and/or metabolic diseases, and/or diseases involving impairment of immune cell functions by administering a compound of formula (Ia).
