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Systems and methods for cell processing
专利权人:
Miltenyi Biotec GmbH
发明人:
MILTENYI, Stefan,SCHIMMELPFENNIG, Winfried,LANTOW, Holger,NEUSCHÄFER, Elmar,BIEHL, Martin,KABAHA, Eiad,SCHULZ, Jürgen
申请号:
ES08857318
公开号:
ES2660180T3
申请日:
2008.12.08
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
A system (100), comprising: a) a sample processing unit (104, 332), comprising a rotating container (500) having at least one sample chamber (128) for containing and processing a sample, in wherein the rotating container (500) comprises means for detecting the progress of the separation (188; 237; 810) of at least a first component and a second component of a sample deposited in the rotating container (500), and a port of input and an output port coupled to the rotating container (500), where the sample processing unit (104, 332) is configured - to rotate the container (500) to apply a centrifugal force to the sample deposited in the chamber ( 128) and separate at least the first component and the second component from the deposited sample; and b) a magnetic sample separation unit (106) coupled to the output port of the sample processing unit (104, 332), the sample separation unit (106) comprises - a separation column holder (42 ), - a pump (64), and - a plurality of valves (1-11; 12, 14, 15, 16; 17; 18; 19; 110; 310, 311; 424, 425; 427, 428, 429) configured to at least partially control the flow of fluid through a fluid circuit, and - a separation column (2; 40; 322) placed in the support (42), wherein the separation column (2; 40; 322) is configured to separate the magnetically labeled and unlabeled sample components that flow through the column (2; 40; 322).Un sistema (100), que comprende: a) una unidad de procesamiento de muestra (104, 332), que comprende un contenedor giratorio (500) que tiene al menos una cámara de muestra (128) para contener y procesar una muestra, en donde el contenedor giratorio (500) comprende un medio para detectar el progreso de la separación (188; 237; 810) de al menos un primer componente y un segundo componente de una muestra depositada en el contenedor giratorio (500), y un puerto de entrada y un puerto de salida acoplado al contenedor giratorio (500), en donde la unidad de procesamiento de muestras (104, 332) se configura - para gir
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