BOWERS PETER,MCKNIGHT ANDREW JOHN,KING DAVID J,LONDEI MARCO
申请号：
IN201717038443
公开号：
IN201717038443A
申请日:
2017.10.30
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the interleukin 36 receptor (IL 36R). The invention provides an IL 36R binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors compositions and methods of using the IL 36R binding agent to treat a disorder or disease that is responsive to IL 36R inhibition such as cancer an infectious disease or an autoimmune disease.
