PERUMAL, OMATHANU P.,AVERINENI, RANJITH KUMAR,PODARALLA, SATHEESH,ALQAHTANI, MOHAMMED
申请号:
CA2828255
公开号:
CA2828255A1
申请日:
2012.02.24
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention encompasses nanoparticle assemblies and methods for preparing nanoparticle assemblies and compositions comprising such assemblies. The invention further encompasses methods of complexing various molecular and cellular entities to the nanoparticles using the resulting nanoparticles of the invention as delivery devices. The nanoparticle assemblies can be used for a variety of applications, such as treating cancer, targeting tumors, reducing the toxicity of a drug in vivo, increasing the efficacy of an complexed agent in vivo, protecting an complexed agent against degradation, and enhancing the water solubility of a drug or other agent.