The present invention relates to a sustained drug-release contact lens. More specifically, the present invention relates to a sustained drug-release contact lens including: a body having cavities configured to be recessed and spaced a predetermined distance apart from each other along a side surface thereof a drug carried in the cavities and a closing part closing each entrance of the cavities where the drug is carried, wherein the closing part biodegrades to open the cavities during wearing of the contact lens, and each closing part of the cavities is configured to open at a different time whereby the cavities are opened sequentially. Thus, the sustained drug-release contact lens releases a predetermined amount of the drug continuously, does not release the drug during storage as the closing parts biodegrade due to an enzyme contained in tears, and can be reloaded with the drug.