ZAJDEL PAWEL,GRYCHOWSKA KATARZYNA,LAMATY FREDERIC,COLACINO EVELINA,BANTREIL XAVIER,MARTINEZ JEAN,PAWLOWSKI MACIEJ,SATALA GRZEGORZ,BOJARSKI ANDRZEJ J,PARTYKA ANNA,WESOLOWSKA ANNA,KOS TOMASZ,POPIK PIOTR
申请号：
IN201617005120
公开号：
IN201617005120A
申请日:
2016.02.15
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
This invention concerns pyrroloquinoline derivatives as antagonists of 5 HT6 receptors to methods for the preparation of these compounds and to novel intermediates useful for their synthesis. The invention also relates to the uses of such compounds and compositions particularly their use in administering them to patients to achieve a therapeutic effect in schizophrenia anxiety depression maniac depression epilepsy obsessive compulsive disorders mood disorders migraine Alzheimer s disease age related cognitive decline mild cognitive impairment sleep disorders eating disorders anorexia bulimia panic attacks attention deficit hyperactivity disorder attention deficit disorder Parkinson s disease Huntington s disease withdrawal from abuse of cocaine ethanol nicotine or benzodiazepines pain obesity and type 2 diabetes functional bowel disorder Irritable Bowel Syndrome. The compounds have the general formula (XIV) wherein the symbols have the meanings given in the description.
