#$%^&*AU2017101409A420171123.pdf#####ABSTRACT The present invention provides a cosmetic composition comprising C-terminal pentapeptide of osteogenic growth peptide, as well as at least one of a carrier, a diluent and an adjuvant. The cosmetic composition of the present invention can promote proliferation of fibroblastic cells and synthesis of skin collagen, and also has remarkable effects of promoting skin wound healing and eliminating swelling and inflammation.