Of diseases telomerase inhibitory effect growth inhibitory effect selective including: (Lash leaf extract from ashwagandha), anti-mutagenic effects, anti-genotoxic activity, tumor cells, or p53 activation activity, is associated with Ashwagandha leaf extract composition for preventing or therapeutic. Aging composition for preventing or anti-aging medicalm including Ashwagandha leaf extract, anti-aging effect on normal cells is associated. Of diseases telomerase inhibitory effect growth inhibitory effect selective including other compounds and U~izanon or (Withanone) itself, anti-mutagenic effects, anti-genotoxic activity, tumor cells U~izanon, or p53 activation activity, is associated composition for preventing or therapeutic. Aging composition for preventing or anti-aging, including medical and other compounds U~izanon or (Withanone) itself, anti-aging effects on normal cells U~izanon is associated.アシュワガンダ葉抽出物(leaf extract from ashwagandha: Lash)を含む、抗変異原性作用、抗遺伝毒性作用、腫瘍細胞に選択的な増殖阻害作用、p53活性化作用、もしくはテロメラーゼ阻害作用が関連する疾患の治療用または予防用組成物。アシュワガンダ葉抽出物を含む、正常細胞に対する抗老化作用が関連する抗老化医療用んまたは老化予防用組成物。ウィザノン(Withanone)それ自身またはウィザノン及び他の化合物を含む、抗変異原性作用、抗遺伝毒性作用、腫瘍細胞に選択的な増殖阻害作用、p53活性化作用、もしくはテロメラーゼ阻害作用が関連する疾患の治療用または予防用組成物。ウィザノン(Withanone)それ自身またはウィザノン及び他の化合物を含む、正常細胞に対する抗老化作用が関連する抗老化医療用または老化予防用組成物。