The bioactive substance a method of impregnating the polymer, preparing bioactive metal, the first solvent bioactive metal is insoluble, and bioactive metal bioactive metal solution comprising a second solvent which sparingly soluble the method comprising. The method also includes the step of immersing the polymer in the bioactive metal solution. Immersion Another method of impregnating a bioactive agent in a polymer, after immersing the polymer in a swelling solvent, bioactive metals, and biological active metal to the polymer to the bioactive metal solution comprising sparingly soluble solvent comprising the step of. Bioactive metal-impregnated polymer is prepared by immersing bioactive metal, the bioactive metal is insoluble expanded solvents, and the polymer in a saturated bioactive metal solution comprising a bioactive metal is slightly-soluble second solvent that.生体活性物質をポリマーに含浸させる方法であって、生体活性金属、生体活性金属が不溶な第1溶媒、および生体活性金属が僅かに可溶な第2溶媒を含む生体活性金属溶液を調製する工程を含む方法。本方法は、生体活性金属溶液中にポリマーを浸漬する工程も含む。ポリマーに生体活性物質を含浸させる別の方法として、該ポリマーを膨潤溶媒に浸漬した後、生体活性金属、および生体活性金属が僅かに可溶な溶媒を含む生体活性金属溶液中に該ポリマーを浸漬する工程を含む。生体活性金属含浸ポリマーは、生体活性金属、生体活性金属が不溶な膨張溶媒、および生体活性金属が僅かに可溶な第2溶媒を含む飽和生体活性金属溶液中にポリマーを浸漬することで調製される。
