PROBLEM TO BE SOLVED: To provide a medicine comprising, as an active ingredient, a natural organic compound that inhibits the differentiation of a preadipocyte to an adipocyte.SOLUTION: As Kalkipyrone, which is derived from cyanobacterium and is represented by the following chemical formula, has the activity to inhibit the differentiation of a preadipocyte to an adipocyte and the activity to inhibit weight gain, an antiobestic agent of the present invention comprises the Kalkipyrone as an active ingredient. The antiobestic agent can inhibit weight gain.SELECTED DRAWING: Figure 4COPYRIGHT: (C)2016,JPO&INPIT【課題】前駆脂肪細胞の脂肪細胞への分化阻害効果を有する天然有機化合物を有効成分として含有する医薬を提供すること。【解決手段】藍藻由来の下記化学式で示されるカリキピロン(Kalkipyrone)が前駆脂肪細胞の脂肪細胞への分化阻害活性および体重増加の抑制活性を有することから、かかる化合物を有効成分として含有する抗肥満薬および体重増加を抑制することを特徴とする抗肥満薬。【選択図】図4
