Nico Callewaert,Bram Laukens,Loes Van Schie,Wander Van Breedam,Wim Nerinckx
申请号：
US16612476
公开号：
US20200148790A1
申请日:
2018.05.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides nucleotide sequences encoding polypeptides comprising immunoglobulin variable domains with engineered glycosylation acceptor sites. Specifically, the invention provides immunoglobulin variable domain proteins modified with selected glycans and specific glycan-conjugates thereof. Also provided herein are methods for the production of glycosylated immunoglobulin variable domains and glycan-conjugates thereof.
