Padval, Mahesh V.,Gautschi, Jeff T.,Smithey, Daniel T.,Crew, Marshall D.,Harianawala, Abizer
申请号:
AU2012225459
公开号:
AU2012225459A1
申请日:
2012.03.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to formulations and methods for increasing the bioavailability of 1- (4-benzhydrylpiperazin-l-yl)-3,3-diphenylpropan-l-one, l-(3,3-diphenylpropanoyl)piperazine, or a salt thereof. In particular, the formulation can include one or more pharmaceutically acceptable matrix polymers to form a solid dispersion, e.g., a spray dried dispersion or a hot melt extrusion.