Abizer Harianawala;Jeff T. Gautschi;Daniel T. Smithey;Marshall D. Crew;Mahesh V. Padval
发明人:
Mahesh V. Padval,Jeff T. Gautschi,Daniel T. Smithey,Marshall D. Crew,Abizer Harianawala
申请号：
US13414369
公开号：
US20130035345A1
申请日:
2012.03.07
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to formulations and methods for increasing the bioavailability of 1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one, 1-(3,3-diphenylpropanoyl)piperazine, or a salt thereof. In particular, the formulation can include one or more pharmaceutically acceptable matrix polymers to form a solid dispersion, e.g., a spray dried dispersion or a hot melt extrusion.
