Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
发明人:
申请号:
EP09718483.2
公开号:
EP2262778B1
申请日:
2009.03.05
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to Formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40, and to their use in a method for treating or preventing diseases based on the expression of MCP-1, CX3CR1 and p40.