An anti-inflammatory and an immunogenic composition for use in providing a synergistic effect for the treatment of a cancer situated in a specific organ or tissue in a human patient, by a method comprising:selecting at least one microbial pathogen that is pathogenic in the specific organ or tissue of the patient within which the cancer is situated;producing an antigenic composition comprising antigenic determinants that together are specific for the microbial pathogen; and,formulating the antigenic composition for administration as an immunogenic composition capable of eliciting an immune reaction to treat the cancer in the patient, andadministering the anti-inflammatory and the immunogenic composition to the patient.