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Transdermally Absorbable Preparation Containing Basic Anti-Inflammatory Analgesic
专利权人:
Akiko Katayama;Katsuyuki Inoo
发明人:
Akiko Katayama,Katsuyuki Inoo
申请号:
US13516094
公开号:
US20120322840A1
申请日:
2010.12.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A transdermally absorbable preparation in which a basic anti-inflammatory analgesic is formulated is provided to be an external adhesive patch, which has excellent drug releasing without damaging the physical properties of a plaster. The preparation can achieve high releasing of the basic anti-inflammatory analgesic without losing the releasing of the local anesthetic. Specifically provided is a transdermally absorbable adhesive patch, which contains both the basic anti-inflammatory analgesic and the local anesthetic as the absorption promoter for the basic anti-inflammatory analgesic. The basic anti-inflammatory analgesic has the acid dissociation constant (pKa) of 7 or more. The content of the basic anti-inflammatory analgesic is from 0.1% to 10% by weight to the total weight of the drug-containing plaster, and the content of the absorption promoter is from 0.01% to 20% by weight to the total weight of the drug-containing plaster in the transdermally absorbable adhesive patch.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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