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Medical use of cell membrane permeable fibroblast growth factor
专利权人:
国立研究開発法人放射線医学総合研究所
发明人:
中山 文明,梅田 禎子,安田 武嗣,藤田 真由美,今井 高志
申请号:
JP2014510567
公开号:
JP5818977B2
申请日:
2013.11.11
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
The present invention relates to a chimeric protein formed by fusing a CPP containing a CPP-C domain in any of an FGF11, FGF12, FGF13, and FGF14 to an FGF1 or an FGF2, or DNA molecules that contain DNA sequences coding the FGF1 or the FGF2 and DNA sequences coding a CPP-C or vectors containing these DNA sequences. These chimeric protein, DNA molecules, or vectors can be used for a medicine or a method of treatment effective to a tissue on which an expression of an FGFR is low or becomes low due to any cause, a medicine or a method of treatment that can further dynamize bioactivity of the FGF1 or the FGF2 via the FGFR, or a medicine or a method of treatment that protects a stem cell against an influence from radiation exposure, a chemotherapy, or a similar treatment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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