Compound of formula (I) ** ** Formula wherein X represents O or S, R1 represents -aryl (C6-C10) or 5- to 10-membered aryl may be substituted (C6-C10) heteroaryl and 5 to 10 members with 1 or 2 substituents selected independently from the group halogen, nitro, cyano, (C1-C6) alkyl, trifluoromethyl, hydroxy, (C1-C6), amino, mono-alkyl (C1-C6) alkylamino, di-alkyl- (C1-C6) alkylamino, hydroxycarbonyl, alkoxy (C1-C6) alkoxycarbonyl, aminocarbonyl, mono-alkyl (C1-C6) alkylaminocarbonyl, di-alkyl- (C1-C6) aminocarbonyl, cycloalkyl (C3-C7) aminocarbonyl, aminosulfonyl, mono-alkyl (C1-C6) alkylaminosulfonyl, di-alkyl- (C1-C6) alkylaminosulfonyl, (C1-C6) alkylsulfonylamino, pyrrolidino , piperidino, morpholino, piperazino, N-alkyl- (C1-C4) -piperazine, pyrrolidinocarbonyl, piperidinocarbonyl, morpholinocarbonyl, piperazinocarbonyl, N-alkyl- (C1-C4) -piperazinocarbonilo and -L-R5 wherein L represents a bond, NH or O, R 5 represents phenyl or 5- or 6 members, wherein phenyl and 5- or 6-membered, in turn, may be substituted with 1 to 3 substituents selected independently from the group halogen, nitro, cyano, (C1-C6) alkyl, trifluoromethyl, hydroxy, alkoxy (C1-C6) alkyl, difluoromethoxy, trifluoromethoxy, amino, mono-alkyl (C1-C6) alkylamino, dialkyl- (C1-C6) alkylamino, hydroxycarbonyl and alkoxy- (C1-C6) alkoxycarbonyl, R2 represents hydrogen or (C1-C4), R3 represents phenyl or 5- or 6-membered, substituted phenyl and can be heteroaryl or 6 members with 5 1 to 3 substituents seleccionadosindependientemente another from the group halogen, cyano, hydroxy, (C1- C6), alkoxy (C1-C6) -alkoxy, (C3-C7), tetrahydrofuranyloxy, pyrrolidinyloxy and -NRARB, wherein (C1-C6) alkoxy (C1-C6) may be substituted with 1 to 3 seleccionadosindependientemente substituents between another group of fluorine, trifluoromethyl, (C3-C7), hydroxy, (C1-C4), hydroxycarbonyl, alkoxy- (C1-C4) -alkoxycarbonyl, amino, aminocarbonyl, mono- (C1-C4) alkylamino and di (C1-C4) -alkylamino, and wherein cycloalkoxy (C3