James M. Apgar;Tesfaye Biftu;Xiaoxia Qian;Lan Wei;Danqing Feng;Robert R. Wilkening
发明人:
Robert R. Wilkening,James M. Apgar,Tesfaye Biftu,Danqing Feng,Xiaoxia Qian,Lan Wei
申请号：
US13520653
公开号：
US20120277240A1
申请日:
2011.02.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is directed to novel substituted aminotetrahydrothiopyrans and derivatives thereof of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
