MCWHERTER, Charles A.,MARTIN, Robert Louis,KARPF, David B.,ROBERTS, Brian K.,LORENZ, Douglas Alan,KETNER, Rodney James
申请号：
ES11728490
公开号：
ES2676209T3
申请日:
2011.06.17
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
A solid dispersion comprising 5% to 75% by weight of 5-ethyl-2- {4- [4- (4-tetrazol-1-yl-phenoxymethyl) -thiazol-2-yl] -piperidin-1-yl} -pyrimidine and a water soluble biologically compatible polymer, in which 25% to 100% by weight of 5-ethyl-2- {4- [4- (4-tetrazol-1-lphenoxymethyl) -thiazole-2- yl] -piperidin-1-yl} -pyrimidine is non-crystalline, and wherein said water soluble biologically compatible polymer is cellulose acetate phthalate.Una dispersión sólida que comprende 5 % al 75 % en peso de 5-etil-2-{4-[4-(4-tetrazol-1-il-fenoximetil)-tiazol-2-il]-piperidin-1-il}-pirimidina y un polímero biológicamente compatible soluble en agua, en la que del 25 % al 100 % en peso de la 5-etil-2-{4-[4-(4-tetrazol-1-lfenoximetil)-tiazol-2-il]-piperidin-1-il}-pirimidina es no cristalina, y en la que dicho polímero biológicamente compatible soluble en agua es acetato-ftalato de celulosa.
