And transmitting and receiving light unit 30 with a reference probe 14 and the multiple of the light transmitting probe 12 and the light-receiving probe 13, a second observation signal acquisition unit 25 to obtain a second observation signal indicative of a change over time related to brain activity, the skin blood It comprises a first observation signal acquiring unit 24 that acquires a first observation signal indicating a temporal change concerning the flow, based on the first and second observation signal, the analysis control unit 40 for creating a removal target component removal observation signal an optical living body measuring device 1, the analysis control unit 40, the independent component analysis, a second mixing matrix for separating a plurality of second observation signal to the product of the second mixing matrix and a plurality of second independent component signal removing a preparation unit 44, a first observation signal removal target second independent component signal determining section 46 for extracting a removal target second independent component signals from a plurality of the second independent component signal with the removal target second observation signal by, and a reconstruction unit 47 to create multiple removal target component removal observation signal.複数の送光プローブ12及び受光プローブ13と参照プローブ14を有する送受光部30と、脳活動に関する経時変化を示す第二観測信号を取得する第二観測信号取得部25と、皮膚血流に関する経時変化を示す第一観測信号を取得する第一観測信号取得部24と、第一及び第二の観測信号に基づいて、除去対象成分除去観測信号を作成する解析用制御部40を備える光生体計測装置1であって、解析用制御部40は、独立成分分析により、複数の第二観測信号を第二混合行列と複数の第二独立成分信号との積に分離する第二混合行列作成部44と、第一観測信号を用いて複数の第二独立成分信号から除去対象第二独立成分信号を抽出する除去対象第二独立成分信号決定部46と、除去対象第二観測信号を除去することにより、複数の除去対象成分除去観測信号を作成する再構築部47を備える。
