An injection device including a needle protection system, said injection device including a delivery needle (10) that is provided with a delivery orifice (11), said protection system comprising a removable needle guard (20) that, in a non-dispensing position, is adapted to be arranged on said needle (10) so as to protect and isolate said delivery orifice (11) of said needle (10), said needle guard (20) including an isolator portion (21) made of flexible material, said delivery orifice (11) of the needle (10) being poked into said isolator portion (21) in the non-dispensing position, said needle guard (10) including at least one outwardly-radial projection (25), said protection system further comprising an outer cap (30) that is provided with grip means (35, 35′, 36； 38； 300) that are adapted to co-operate with said at least one radial projection (25) of said needle guard (20), such that moving said outer cap (30) in the longitudinal direction of said needle (10), away from said delivery orifice (11), removes said needle guard (20) from the non-dispensing position, said at least one radial projection (25) being arranged at the distal axial end of said needle guard (20), said at least one radial projection (25) being formed on a rigid outer structure (28) of said needle guard (20).
