Injection device having a needle protection system, said injection device having a dispensing needle (10) provided with a dispensing orifice (11) , said protection system having a removable needle guard (20) which is designed to be arranged on said needle (10), in the non- dispensing position , in order to protect and isolate said dispensing orifice (11) of said needle (10) , said needle guard (20) having an insulating part (21) made of flexible material , said dispensing orifice (11) of the needle (10) being stuck in said insulating part (21) in the non -dispensing position , said needle guard (20) having at least one radial projection (25) towards the outside , said protection system having an external cap (30) provided with gripping means (35 , 35 " 36 38 300) which are designed to cooperate with said at least one radial projection (25) of said needle guard (20), in such a way that a movement of said external cap (30) in the longitudinal direction of said needle (10) away from said dispensing orifice (11) draws said needle guard (20) from its non- dispensing position , said at least one radial projection (25) being arranged at the distal axial end of said needle guard (20), said at least one radial projection (25) being formed on a rigid external structure (28) of said needle guard (20).
