It makes control and to make promote the nucleation of the product inside being manner in order the frozen dehydration device and, in the generation interior of the above-mentioned frozen dehydration device it maintains the above-mentioned product in specified temperature, and specified pressure is separable from the above-mentioned generation chamber, at the same time through the steam port, in the storage interior which is jointed to the above-mentioned generation chamber the ice fog of the specified quantity it generates. The above-mentioned ice fog has had the specified pressure which is higher than pressure of the above-mentioned generation chamber, through the above-mentioned steam port, making the above-mentioned ice fog the above-mentioned generation interior distribute evenly the above-mentioned ice fog by carrying to the above-mentioned generation interior quickly, it makes the nucleation of the above-mentioned product cause uniformly and quickly in the field where the above-mentioned generation chamber differs.凍結乾燥装置内の生成物の核形成を制御および促進させるための方法であって、上記生成物を上記凍結乾燥装置の生成室内で所定温度かつ所定圧力に維持し、上記生成室とは分離しており、かつ蒸気ポートを介して上記生成室に接続された貯蔵室内で所定量の氷霧を生成する。上記氷霧は上記生成室の圧力よりも高い所定圧力を有しており、上記蒸気ポートを介して上記氷霧を上記生成室内に迅速に輸送することにより、上記氷霧を上記生成室内に一様に分散させて上記生成室の異なる領域において上記生成物の核形成を均一かつ急速に生じさせる。