A frozen particulate slurry comprises a first component and a second component which are capable of forming a eutectic mixture. The slurry is formed by cooling a composition comprising the first and second components to a temperature below the freezing point of the first component to form particles of the first component, and then cooling to freeze a eutectic mixture of the first component and the second component. A method of thawing the frozen particulate slurry comprises heating the slurry, and an apparatus for thawing the frozen particulate slurry comprises a container for holding the particulate slurry, a heat source, and an agitator. A method of inducing therapeutic hypothermia in a patient comprises heating the frozen particulate slurry and administering the particulate slurry to the patient in an amount sufficient to locally or systemically induce therapeutic hypothermia.
