A decontamination system for a lumen device is provided. The decontamination system comprises a lumen device container and a sterilant fluid delivery device. The lumen device container defines a lumen device receiving area that includes a fluid connector in fluid communication with the lumen device receiving area. The sterilant fluid delivery device is configured to be in fluid communication with the fluid connector. In some embodiments, the fluid connector is configured to form a loose connection with a port of a lumen device to deliver sterilant fluid into the port and leak sterilant fluid onto an external surface of the port.