A natural composition contains cinnamomum osmophloeum and hawthorn. The cinnamomum osmophloeum refers to the water extract of cinnamomum osmophloeum leaves and the hawthorn refers to the water extract of hawthorn fruits, wherein the weight ratio of the cinnamomum osmophloeum to the hawthorn is 1:0.05~2, preferably 1:0.5~1.5, and best 1:0.9~1.1. The pharmaceutical composition of the present invention has the effect for inhibiting alpha-glucosidase. The natural composition of the present invention may further inhibit alpha-amylase to regulate the absorption of blood sugar and carbohydrate.一種天然組合物,包含土肉桂及山楂,土肉桂係指土肉桂葉的水萃物,山楂係指山楂果實的水萃物,其中土肉桂與山楂的重量比例為1:0.05~2,較佳比例為1:0.5~1.5,最佳比例為1:0.9~1.1。本藥物組合物具有抑制α-葡萄糖苷酶(α-glucosidase)的功效。本天然組合物還可進一步抑制α-澱粉酶(α-amylase),以調控血糖及醣類的吸收。