LV, AI FENG,吕爱锋,呂愛鋒,SUN, CHANG AN,孙长安,孫長安,JIANG, TAO,姜涛,姜濤,WU, WEN TAO,吴文涛,吳文濤,WANG, YA LI,王亚里,王亞里
申请号：
TW097125651
公开号：
TWI419706B
申请日:
2008.07.08
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
This invention relates an erythropoietin mimics derivatives represented by formula (I), medicine salt and preparation thereof, wherein R1, R2, R3, R4, R5, n1, n2are same as the definition in the specification. Further, this invention relates to a pharmaceutical composition comprising the erythropoietin mimics represented by formula (I) and medicine salt thereof. R1-R2-(CH2)n1R3-(CH2)n2-R4-R5(I) According to this invention, the erythropoietin mimics derivatives and medicine salt thereof, or the pharmaceutical composition comprising the erythropoietin mimics derivatives and medicine salt thereof can be widely applied to the diseases characterized by a deficiency of erythropoietin or an absence or deficiency of erythrocytes groups.本發明係有關一種通式(I)所示的促紅細胞生成素模擬肽衍生物及其可藥用鹽以及它們的製備方法，其中R1、R2、R3、R4、R5、n1、n2如說明書所定義。本發明另有關一種含有通式(I)所示的促紅細胞生成素模擬肽衍生物及其可藥用鹽的藥物組合物。本發明提供的促紅細胞生成素模擬肽衍生物及其可藥用鹽或含有促紅細胞生成素模擬肽衍生物及其可藥用鹽的藥物組合物可在治療以缺乏紅細胞生成素或紅細胞群缺少或缺陷為特徵的疾病中廣泛應用。R1-R2-(CH2)n1-R3-(CH2)n2-R4-R5 (I)
