JINHONG CHANG,FANG GUO,TIMOTHY M. BLOCK,JU-TAO GUO
申请号：
US15483645
公开号：
US20170281589A1
申请日:
2017.04.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided herein are methods of treating a subject having hepatitis B viral (HBV) infection. More specifically, disclosed herein are methods of stimulating the innate cytokine response in macrophages, dendritic cells and/or liver non-parenchymal cells with small molecular agonists of STING to suppress HBV replication in hepatocytes. The methods are especially suitable for use in the treatment of chronic HBV infections. Also disclosed herein are methods of identifying compounds useful in the treatment of HBV infection.
