Jinhong Chang,Fang Guo,Timothy M. Block,Ju-Tao Guo
申请号：
US15028813
公开号：
US09642830B2
申请日:
2014.10.21
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention includes methods of treating a subject having hepatitis B viral (HBV) infection. In certain embodiments, the method of the invention comprises stimulating the innate cytokine response in macrophages, dendritic cells and/or liver non-parenchymal cells with small molecular STING agonists, thus suppressing HBV replication in hepatocytes. In other embodiments, the method of the invention can be used to treat chronic HBV infections. The invention further provides methods of identifying compounds useful in treating HBV infection in a subject.
