A method for relief of pain comprises applying skin stimulation along one or two treatment lines traversing vertically the scalp of the subject above the eyes thereof. Skin stimulation may be accomplished by one or several techniques including acupuncture, corona discharge, applying an electromagnetic field, massaging, vibration, subcutaneous injection of stimulating fluids, light, or heating. Suitable head-mounted devices supporting skin stimulation units are described to allow self-use by the subject itself or the method to be administered by a medical personnel.