Beatriz Llano-Sotelo,Alexander S. Mankin,Dorota Klepacki
申请号：
US12673283
公开号：
US08648035B2
申请日:
2008.08.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention discloses compositions of peptide inhibitors of protein synthesis, and methods of identifying peptide inhibitors that are capable of inhibiting protein synthesis through an interaction at a stem-loop H18 in 16S rRNA of a 30S ribosomal subunit. Screening methods for peptides are disclosed, in addition to methods of determining the affinity of a test compound for a ribosomal subunit.
