A colonoscope handle attachment device includes a body having arms sized to couple with the colonoscope and a hook that is sized to receive another portion of the colonoscope therein, such as the endoscope shaft. The hook defines a U-shaped channel that can be angled relative to a primary longitudinal axis of the body. However, the U-shaped channel can also be oriented as offset parallel to the primary longitudinal axis of the body. The configuration of the device allows an operator of the colonoscope, such as a physician, to have a free hand to perform other tasks inasmuch as the hook holds or couples the other portion or sub-component of the colonoscope near the handle of the colonoscope. At least portions of the body and the hook are at least semi-flexible to allow the device to releasably connect with the handle of the colonoscope.