Breitenbach, Jorg,Westedt, Ulrich,Ogorka, Jorg,Altenburger, Ralf,Steiger, Norbert,Knobloch, Martin,Loggia, Nicoletta,Hach, Harald
申请号:
AU2007316557
公开号:
AU2007316557B2
申请日:
2007.11.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The invention provides a dosage form, comprising a melt-processed mixture of (a) a pharmaceutically effective amount of imatinib or a salt thereof, (b) at least one polymeric binder, and (c) at least one pharmaceutically acceptable non-ionic surfactant. The invention provides imatinib dosage forms with high drug loading which can be prepared in a simple and efficient manner, imatinib dosage forms from which the active principle is released in an essentially pH-independent fashion, and extended release imatinib dosage forms.