COMPOSÉS THÉRAPEUTIQUES

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专利权人:

MERCK SHARP & DOHME CORP.;MSD K.K.

发明人:

KATZ, JASON,JEWELL, JAMES,JUNG, JOON,KATTAR, SOLOMON,HOU, YONGQUAN,MACCOSS, RACHEL,ITO, SATORU

申请号：

EP09805357

公开号：

EP2320907A4

申请日:

2009.07.27

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention relates to pyrazolopyridines and imidazopyridines which are inhibitors of the kinase PDK1 and are thus useful for the treatment of myeloproliferative disorders or cancer. The compounds are also useful as inhibitors of other kinases such as FGFR3, NTRK3, RP-S6K and WEE1. Furthermore, the present compounds also selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/