Mary ERICKSON,David C. LITZINGER,Soumitra S. GHOSH,Zijian GUO,Manoj P. SAMANT,Abhinandini SHARMA,Lala MAMEDOVA,Odile Esther LEVY,Caroline EKBLAD
申请号：
US15177397
公开号：
US20180344813A1
申请日:
2016.06.09
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compounds are provided having inter alia good duration of action, high potency and/or convenient dosing regimens including oral administration, and reduced immunogenicity. The compounds are engineered polypeptides which incorporate an albumin binding domain in combination with one or more biologically active polypeptides. Also provided are pharmaceutical compositions and methods of treatment for diseases and disorders including obesity and overweight, diabetes, dyslipidemia, hyperlipidemia, Alzheimers disease, fatty liver disease, Short Bowel Syndrome, Parkinsons disease, and cardiovascular disease.
