WINTERS, Geoffrey C.,MANDEL, Alexander Laurence,RICH, James R.,HEDBERG, Bradley John,HSIEH, Tom Han Hsiao,BOURQUE, Elyse Marie Jose,BABCOOK, John
申请号：
HK16108315.3
公开号：
HK1220140A
申请日:
2016.07.15
申请国别(地区):
HK
年份:
2017
代理人:
摘要：
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
