The present invention relates to compounds of the general formula II or salts or solvates thereof, as well as to the medical uses to which they are concerned and to a process for the production of such compounds, wherein A 1 is selected from the group consisting of N and CR 8 , ； A <； 2 >； is selected from the group consisting of N and CR <； 3 >；； A <； 3 >； is selected from the group consisting of N and CR <； 9 >；； A 4 and A 5 and A 6 are independently selected from the group consisting of N and CR 1 ； R 1 is selected from the group consisting of hydrogen, (C 1 -C 3 ) alkyl, halogen, (C 1 -C 3 ) alkoxy, and (C 1 -C 3 ) haloalkyl； R 2 is selected from the group consisting of hydrogen, halogen, and (C 1 -C 3 ) alkyl； R 3 is selected from the group consisting of hydrogen, (C 1 -C 3 ) alkyl, NR 4 R 5 , (C 1 -C 3 ) alkyl-NR 4 R 5 and cyano, wherein R 4 and R 5 are independently Is selected from the group consisting of hydrogen, (C 3 -C 5 ) cycloalkyl, (C 3 -C 5 ) heterocycloalkyl and (C 1 -C 3 ) alkyl, or R 4 and R 5 are selected from the group consisting of nitrogen Together with the atoms form a 5- to 7-membered heterocyclic ring, wherein the 5- to 7-membered heterocyclic ring optionally contains, in addition to the above-mentioned nitrogen atom, optionally O and NR 6 , wherein R 6 is hydrogen, Methyl, acetyl, and formyl； and R <； 2 >； Y is selected from the group consisting of O and S； R 8 is selected from the group consisting of (C 1 -C 4 ) alkyl, (C 3 -C 5 ) cycloalkyl and (C 3 -C 5 ) heterocycloalkyl； R 9 is selected from the group consisting of hydrogen, (C 1 -C 3 ) alkyl and (C 1 -C 3 ) alkoxy； Certain specific compounds are excluded conditionally. <； RTI ID = 0.0 &본 발명은 일반 화학식 II의 화합물 또는 이의 염 또는 용매화물뿐만 아니라, 이들이 관여하는 의학적 용도, 및 그러한 화합물의 생성 방법에 관한 것으로서, 화학식 II에서, A1은 N 및 C-R8로 이루어진 군으로부터 선택되고； A2는 N 및 C-R3으로 이루어진 군으로부터 선택되고； A3은 N 및 C-R9로 이루어진 군으로부터 선택되고； A4 및 A5 및 A6은 독립적으로 N 및 C-R1로 이루어진 군으로부터 선택되고； R1은 수소, (C1-C3)알킬, 할로겐, (C1-C3)알콕시, 및 (C1-
