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Lck-derived peptide useful for cancer vaccine therapy for HLA-A3 supertype allele positive cancer patients
专利权人:
株式会社グリーンペプタイド
发明人:
伊東 恭悟,野口 正典,原田 守
申请号:
JP2009528113
公开号:
JP4972691B2
申请日:
2008.08.08
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
Disclosed is an Lck-derived peptide which is useful for the treatment or prevention of a cancer patient who is positive for an HLA-A3 supertype allele. Specifically disclosed are peptides of Lck90-99, Lck449-458 and Lck450-458 (SEQ ID NOs: 4, 17 and 18). These peptides can bind to an HLA-A3 supertype allele molecule and has a peptide-specific CTL-inducing ability. These peptides are particularly useful for the treatment of a cancer patient who is negative for an HLA-A2 or HLA-A24 molecule for which many cancer vaccine candidate peptides have been identified so far.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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