Robert Lambkin-Williams,John S. Oxford,Thomas Wilkinson
申请号:
US13336648
公开号:
US20130164315A1
申请日:
2011.12.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides a screening method for identifying a peptide capable of inducing a T cell response comprising:a) contacting a peptide having a level of identity with a sequence of a protein of a virus, with a test sample comprising T cells obtained from blood from a subject who is currently or has been recently infected with the virus,b) quantifying the response of the T cells to the peptide,c) comparing the T cells response in b) to a response of a control sample comprising T cells obtained from blood from a subject who is not currently infected nor been recently infected with the virus, when contacted with the peptide,wherein a greater response to the peptide in b) than in c) is indicative of a peptide capable of inducing a T cell response.