Enzyme conjugate and prodrug cancer therapy
- 专利权人:
- 发明人:
- Roger G. Harrison, Jr.,John J. Krais
- 申请号：
- US14865650
- 公开号：
- US09987241B2
- 申请日:
- 2015.09.25
- 申请国别(地区):
- US
- 年份:
- 2018
- 代理人:
- 摘要：
- A method and composition for treating a cancerous tumor in a subject by targeting the tumors vasculature using an enzyme conjugate comprising a ligand which binds to endothelial cells in the tumor vasculature and converts a prodrug administered to the subject into an anticancer drug in the tumor vasculature.
- 来源网站：
- 中国工程科技知识中心
相关发明人
相关专利
- Enzyme prodrug cancer therapy selectively targeted to tumor vasculature and methods of production and use thereof
- NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES
- NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES
- Conjugates of polymers having a therapeutically active agent and an angiogenesis targeting moiety attached thereto and uses thereof in the treatment of angiogenesis related diseases
- NITROFURAN COMPOUNDS FOR THE TREATMENT OF CANCER AND ANGIOGENESIS
