NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES
Fundacion de la Comunidad Valenciana Centro de Investigacion Principle Felipe;Ramot at Tel-Aviv University Ltd.
发明人:
Ronit SATCHI-FAINARO,Maria Jesus Vicent Docon
申请号：
US14082224
公开号：
US20140079638A1
申请日:
2013.11.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Conjugates of a polymer having attached thereto an angiogenesis targeting moiety and a therapeutically active agent such as an anti-cancer agent or anti-angiogenesis agent, and processes of preparing same are disclosed.Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of angiogenesis-related medical conditions such as cancer and cancer metastases are also disclosed.
