Общество с ограниченной ответственностью "Инновационные полимерные адгезивы" (RU)
发明人:
Фельдштейн Михаил Майорович (RU),Перепелица Галина Григорьевна (RU),Хохлов Алексей Ремович (RU)
申请号：
RU2012116982/15
公开号：
RU2012116982A
申请日:
2012.04.27
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A hydrophilic pressure-sensitive bioadhesive, which is a non-covalent complex of a film-forming polymer, with at least one of the following complementary components: a polymer crosslinking agent, an oligomeric crosslinking agent, a low molecular weight substance, or a mixture of at least two of these components, where the film-forming the polymer and the polymer crosslinking agent are selected from the class of hydrophilic polymers, while the components of the bioadhesive are taken in an amount that provides the complex, which adheres to adhesion to the surface of the teeth and the absence of stickiness to other tissues in the oral cavity, with the following parameters: glass transition temperature in the swollen state - from -10 to -130 ° C, the elastic modulus G 'in the swollen state is less than 0.45 MPa, the loss tangent is the swollen state is from 0.60 to 1.20, the degree of swelling in the aquatic environment for 10 minutes is from 0.1 to 0.7, the swelling limit is from 1 to 15.2. Bioadhesive according to claim 1, characterized in that it further comprises at least one plasticizer. The bioadhesive according to claim 1, characterized in that the film-forming polymer and a crosslinking agent are taken in a mass ratio of from 3: 1 to 1: 1.4. Bioadhesive according to claim 1, characterized in that the film-forming hydrophilic polymer is present in the mixture at a concentration of 20-90 wt.%, Preferably 30-80 wt.% And more preferably 40-60 wt.%. 5. Bioadhesive according to claim 1, characterized in that the glass transition temperature is measured using differential scanning calorimetry in heating mode at a speed of 20 ° / min. The bioadhesive according to claim 1, characterized in that a polyacid is used as the film-forming polymer, and1. Гидрофильный чувствительный к давлению биоадгезив, представляющий собой нековалентный комплекс пленкообразующего полимера, по крайней мере с одним из следующих комплементарных компонентов:полимерным сшивающим агентом,олигоме
