Закрытое акционерное общество "Московская фармацевтическая фабрика" (RU)
发明人:
Дулькис Мария Дмитриевна (RU),Сапожкова Мария Борисовна (RU)
申请号：
RU2012145238/15
公开号：
RU2012145238A
申请日:
2012.10.25
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. Medicament having venotonicheskim and anticoagulant effect, comprising grape leaf extract dry basis, preservatives, solvents, characterized in that it further contains heparin as a pharmaceutically acceptable salt thereof, as a basis comprises a hydrophilic gelling agent, as a solvent comprising purified water, propylene glycol, rectified ethyl alcohol of 95% as a preservative - nipagin, Nipasol, with the following ratio of components, wt%: 2.. Medicament according to claim 1, characterized in that the hydrophilic gelling agent comprises redkosshitye acrylic polymers and further comprises a neutralizing agent in an amount of 0.2-2.0 wt.%. 3. Medicament according to any one of claims 1 and 2, characterized in that it further comprises an antioxidant in an amount of 0.01-5.0 wt.%. 4. Medicament according to any one of claims 1 and 2, characterized in that it additionally comprises a volatile oil in an amount of 0.01-5.0 wt.%. 5. A process for preparing a medicament having venotonicheskim and anticoagulant effect, comprising: a) dissolving nipagin and Nipasol a rectified ethyl alcohol 95% b) adding propylene glycol and purified water, and c) preparation in individual containers of aqueous solutions of extract of vine leaves and dry heparin in the form of pharmaceutically acceptable salt d) mixing the solutions obtained in steps b) and c) and the addition of a hydrophilic gelling agent d) homogenizing, the components are used in amounts, to provide vayuschih drug preparation having the composition of p.1.6. A method according to claim 5, characterized in that in step c) additionally1. Лекарственный препарат, обладающий венотоническим и антикоагулянтным действием, включающий винограда листьев экстракт сухой, основу, консерванты, растворители, отличающийся тем, что дополнительно содержит гепарин в виде фармацевтически приемлемой соли, в качестве основы содержит гидрофильный гелеобразователь, в качестве растворителей содержит воду очищенную, пропиленгликоль, спирт этило
