This Hair is bright to be related to formula (I)-(VII) Xin type Ben and Er Dan Miscellaneous compound with being related to the novel Ben and Er Dan Miscellaneous derivative , And with antiproliferative activity and Geng Ju Body. Ben described in the bright also offer Will of this Hair and Er Dan Miscellaneousization He Wu Even meet what Fine Bao Knot and close Elixirs Suffix conjunction object. The bright It of this Hair provides the bright describedization conjunction Wu Huo Suffix conjunction object what of this Hair of Shi Yong and inhibits the normal Fine Bao Sheng Long of Iso in lactation Move object or control Treatment proliferative disorders Group conjunction object and method.本發明涉及新型具有抗增殖活性的苯并二氮雜䓬衍生物,並且更具體地涉及式(I)-(VII)的新型苯并二氮雜䓬化合物。本發明也提供將所述苯并二氮雜䓬化合物連接於細胞結合劑的綴合物。本發明還提供使用本發明的所述化合物或綴合物用於在哺乳動物中抑制異常細胞生長或治療增殖性病症的組合物及方法。