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DMA-CO-TEMPO POLYMER FOR THERAPEUTIC ROS SCAVENGING
专利权人:
Vanderbilt University
发明人:
Craig L. Duvall,Taylor Kavanaugh,Eric Dailing,Bryan Dollinger,Carlisle Dejulius
申请号:
US16652236
公开号:
US20200247930A1
申请日:
2018.10.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are a reactive oxygen species (ROS) scavenging composition, a method of forming a ROS scavenging composition, and a method of treating a subject having a (ROS) perpetuated disease. The ROS scavenging composition includes a co-polymer of a hydrophilic monomer and a grafting monomer, and a ROS scavenging compound grafted to the grafting monomer. The method of forming a ROS scavenging composition includes forming a co-polymer of a hydrophilic monomer and a grafting monomer, and grafting ROS scavenging compound onto the co-polymer. The method of treating a subject having a ROS perpetuated disease includes administering a therapeutically effective amount of an ROS scavenging composition comprising a co-polymer of a hydrophilic monomer and a grafting monomer, and a ROS scavenging compound grafted to the grafting monomer, to the subject in need thereof.
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