LONG-CIRCULATING ZWITTERIONIC POLYPLEXES FOR siRNA DELIVERY

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专利权人:

VANDERBILT UNIVERSITY

发明人:

Craig L. Duvall,Meredith A. Jackson

申请号：

US16614307

公开号：

US20200171169A1

申请日:

2018.05.15

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Provided herein are a polymer, a polyplex, and a method of treating a disease. The polymer includes a core-forming block and a zwitterionic corona block. The polyplex includes the polymer complexed with an active agent. The method of treating a disease comprises administering the polyplex to a subject in need thereof.

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