Rhythm Pharmaceuticals, Inc.;Charité-Universitätsmedizin Berlin
发明人:
Van Der Ploeg, Leonardus H.T.,Henderson, Bart,Kuhnen, Peter
申请号:
AU2016330773
公开号:
AU2016330773A1
申请日:
2016.09.29
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The disclosure is related to a method of treating a disorder, such as Prader Willi Syndrome (PWS), obesity or hyperphagia, in a subject using a melanocortin-4 receptor (MC4R) agonist. Also described is method of treating a subject having a deficiency in the pro-opiomelanocortin (POMC)-MC4R pathway, such as a POMC-null or a PCSK-null subject, using a MC4R agonist.